Dowload wizard files added and Dil slider update
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This commit is contained in:
2026-08-15 16:40:17 +02:00
parent f154986505
commit e7400fe0fa
+59 -47
View File
@@ -636,7 +636,7 @@ server <- function(input, output, session) {
"Narrower dilution ranges decrease the CIs of rel. potency, and increase the CIs of upper and lower asymptote ratios, ands Hill's slope ratios",
),
tabPanel("Histograms",
tabPanel("Plots",
h4("Histograms of parameters"),
plotOutput("linerangeCIs"),
plotOutput("ratioSlope"),
@@ -658,10 +658,10 @@ server <- function(input, output, session) {
tabPanel(
"Report",
h4("Settings for report"),
useShinyjs(),
actionButton("btn2", "Download PDF report", icon = icon("download")),
downloadButton("downloadWizardReport", label = "Download report", class = "butt"),
tags$style(type = "text/css", "#downloadWizardReport {background-color: #4FCBD9; color: black;font-family: Courier New}"),
#useShinyjs(),
#actionButton("btn2", "Download PDF report", icon = icon("download")),
downloadButton("downloadWizardData", label = "Download model and plots", class = "butt"),
tags$style(type = "text/css", "#downloadWizardData {background-color: #4FCBD9; color: black;font-family: Courier New}"),
# textInput("Author", "Author", value = ""),
# textInput("RepIdentifier", "Report name", value = ""),
# textInput("NoP", "Product name", value = ""),
@@ -2235,15 +2235,17 @@ server <- function(input, output, session) {
ratioDF <- data.frame(WS_name = URMcoefsDF[,1], slopeRatio = slopeRatio, LasRatio = LasRatio, UasRatio = UasRatio)
RMcoefsDF <- t(matrix(unlist(RMcoefsL),nrow=6))
colnames(RMcoefsDF) <- c("WS name", "lower asymptote","Hill's slope","upper asymptote","log(EC50 ref)","logEC50 difference")
Dat$URMcoefsDF <- URMcoefsDF
Dat$ModU <- URMcoefsDF
Dat$RestrM <- RMcoefsDF
Dat$ModR <- RMcoefsDF
CalcPotDF <- t(matrix(unlist(potEstL),nrow=3))
colnames(CalcPotDF) <- c("rel_potency","lower_CI","upper_CI")
Dat$CalcPot <- CalcPotDF
#
#### sigmoid plots ----
#### Wizard sigmoid plots ----
Slope <- as.numeric(URMcoefsDF[1,3])
if (Slope > 0) {
@@ -2484,12 +2486,15 @@ server <- function(input, output, session) {
if (!is.null(p2)) {
#p2 <- Dat$p2
p_dil <- p2 +
annotate("pointrange", x = dils2, y = rep(min_y, length(dils2)), xmin = min(dils2), xmax = max(dils2),colour = "red" ,linetype = 3) +
geom_vline(xintercept = dils2, col = "red", linetype = 2, alpha=0.5) +
annotate("pointrange", x = dils2, y = rep(min_y, length(dils2)), xmin = min(dils2), xmax = max(dils2),
colour = "red" ,linetype = 3, shape=24) +
annotate("text", x = dils2, y = rep(min_y + (max_y - min_y) * 0.05, length(dils2)), label = as.character(round(dils2, 3)),colour = "red") +
annotate("text",
x = dils2[-1] + (max(dils2) - min(dils2)) * 0.05,
y = rep(min_y + (max_y - min_y) * 0.1, length(dils2[-1])),
label = as.character(round(dilfactors[-1], 3)),colour = "red")
label = as.character(round(dilfactors[-1], 3)),colour = "red")
# geom_line(
# data = as.data.frame(pl_df), aes(x = dils2, y = SAMPLE50), color = "grey15", linetype = 2,
# inherit.aes = F
@@ -2498,24 +2503,7 @@ server <- function(input, output, session) {
# data = as.data.frame(pl_df), aes(x = dils2, y = SAMPLE200), color = "grey15", linetype = 2,
# inherit.aes = F
# ) +
# geom_vline(xintercept = c(Xbend50, Xbend200), col = "grey15", linetype = 2) +
# { if (input$scenario == "scenario 6") {
# annotate("pointrange",
# x = optdils2, y = rep(min_y + (max_y - min_y) * 0.2, length(optdils2)),
# xmin = min(optdils2), xmax = max(optdils2), color = "seagreen"
# )
# }
# } +
# {
# if (input$scenario == "scenario 6") {
# annotate("text",
# x = optdils2, y = rep(min_y + (max_y - min_y) * 0.25, length(optdils2)),
# label = as.character(round(optdils2, 3)), color = "seagreen"
# )
# }
# } +
# annotate("text",
# x = optdils[1], y = (max_y + min_y) * 0.5,
# label = paste("in green: optimal \n dilutions acc. to Whitepaper\n", input$scenario), color = "seagreen",
@@ -2525,6 +2513,7 @@ server <- function(input, output, session) {
print(p_dil)
})
Dat$DilPlot <- p_dil
} # if (!is.null(p2))
} # if !is.null Dat$Mws
@@ -2892,30 +2881,53 @@ server <- function(input, output, session) {
#### download Wizard report ----
output$downloadWizardReport <- downloadHandler(
filename = paste0("Report_Meta", Dat$nameRep, ".pdf"),
output$downloadWizardData <- downloadHandler(
filename = paste0("CompiledData", Dat$nameRep, ".zip"),
content = function(file) {
fs <- c()
tpdr <- tempdir()
tempReport <- file.path(tpdr, "Doc_BioassayLinReport.Rmd")
file.copy("Doc_BioassayLinReport.Rmd", tempReport, overwrite = TRUE)
filename = paste0("CompiledData", Dat$nameRep, ".zip")
#tempReport <- file.path(tpdr, "Doc_BioassayLinReport.Rmd")
#file.copy("Doc_BioassayLinReport.Rmd", tempReport, overwrite = TRUE)
tempReportc <- file.path(tpdr, "logov2.png")
file.copy("logov2.png", tempReportc, overwrite = TRUE)
#tempReportc <- file.path(tpdr, "logov2.png")
#file.copy("logov2.png", tempReportc, overwrite = TRUE)
rmarkdown::render(tempReport,
output_file = file,
params = list(
FileName = Dat$FileName,
author = Dat$Author,
NoP = Dat$NoP,
Assay = Dat$Assay,
REP = REP,
REPlin = REPlin,
coeffsLin = Dat$coeffs_UN
),
envir = new.env(parent = globalenv())
)
}
# rmarkdown::render(tempReport,
# output_file = file,
# params = list(
# FileName = Dat$FileName,
# author = Dat$Author,
# NoP = Dat$NoP,
# Assay = Dat$Assay,
# REP = REP,
# REPlin = REPlin,
# coeffsLin = Dat$coeffs_UN
# ),
# envir = new.env(parent = globalenv())
# )
#browser()
fileOutModU=paste(paste0(tpdr, sep='/', 'unrModelFits'), sep='','.csv')
fs=c(fs, fileOutModU)
ModU <- Dat$ModU
write.csv(ModU, fileOutModU, row.names = F)
fileOutModR=paste(paste0(tpdr, sep='/', 'restrModelFits'), sep='','.csv')
fs=c(fs, fileOutModR)
ModR <- Dat$ModR
write.csv(ModR, fileOutModR, row.names = F)
DilPlot <- Dat$DilPlot
fileOutDilPlot =paste(paste0(tpdr, sep='/', 'SigmoidDilutionsPlot'), sep='','.png')
fs=c(fs, fileOutDilPlot)
png(fileOutDilPlot, width=600, height=400)
print(DilPlot)
dev.off()
#browser()
zip::zipr(zipfile=file, files=fs, include_directories = F)
}, contentType = "application/zip"
)
}